Leland Kaiser in 1992 introduced the term regenerative medicine by providing a new branch of medicine that aims to address chronic diseases and the replacement of aged and functionally deficient organs. Since then, many researchers in all parts of the world are trying to develop cell therapies aimed at regeneration of injured or degenerated tissue.

When there is injury to connective tissue structures such as muscles, tendons, ligaments or articular cartilage, the body activates repair mechanisms available to heal the damage.

Unfortunately, in some cases, especially in areas where blood flow is reduced or blocked, as happens in and around the joints, the body cannot do it and by consequence adequately correct the fault.

Thus, there is a persistent and constant pain, weakness and swelling that eventually lead to difficulty in use in the region or member suffering.


Biological therapies are aimed to enhance the natural process of healing to cure or improve the damaged tissue.

A great deal of Orthopaedic Research, has focused on these treatments which makes them the big bet for the future. Essentially, it is a revolutionary way of addressing injuries and diseases of the musculoskeletal, and a promise to postpone or at least delay surgical treatment.

These therapies are used to treat orthopedic diseases such as the following:

✓ Arthritis hip, knee, shoulder, ankle and small joints of the hand

✓ Injury or diseases of articular cartilage – Injury or disease intra-articular structures

✓ Chronic tenontopatheies (rotator cuff, patellar and Achilles tendon)

✓ Chronic elbow epicondylitis (Tennis elbow or golfer’s elbow) – Injury links (eg. Acromioclavicular)

✓ Muscle contusions or stretching athletes

These interventions are surgical or not, and are intended to heal and to regenerate the tissue: the noninvasive can be performed in the office, whose main representative injecting autologous healing factors or PRP from the initials of Plasma Rich Platelet.


Surgical solutions include autologous transplantation of chondrocytes, the use of natural polymers such as Chitosan and injection of stem cells (stem cells). These interventions combine with arthroscopy, thereby reducing morbidity on the application of open surgery.